Özcan Lab Publications

Journal Articles

  1. Özcan, S., K. Freidel, A. Leuker, and M. Ciriacy. 1993. Glucose uptake and catabolite repression in dominant HTR1 mutants of Saccharomyces cerevisiae. J. Bacteriol. 175:5520-5528.
  2. Özcan, S., F. Schulte, K. Freidel, A. Weber, and M. Ciriacy. 1994. Glucose uptake and metabolism in grr1/cat80 mutants of Saccharomyces cerevisiae. Eur. J. Biochem. 224:605-611.
  3. Özcan, S., and M. Johnston. 1995. Three different regulatory mechanisms enable yeast hexose transporter (HXT) genes to be induced by different levels of glucose. Mol. Cell. Biol. 15:1564-1572.
  4. Özcan, S., and M. Johnston. 1996. Two different repressors collaborate to restrict expression of yeast glucose transporter genes HXT2 and HXT4 to low levels of glucose. Mol. Cell. Biol. 16:5536-5545.
  5. Özcan, S., S., T. Leong, and M. Johnston. 1996. Rgt1p of Saccharomyces cerevisiae, a key regulator of glucose-induced genes, is both an activator and a repressor of transcription. Mol. Cell. Biol. 16:6419-6426.
  6. Özcan, S., J. Dover, A. G. Rosenwald, S. Wolfl, and M. Johnston. 1996. Glucose sensing and signal-generation by two glucose transporters in S. cerevisiae. Proc. Natl. Acad. Sci. USA 93:12428-12432.
  7. Özcan, S., L. G. Vallier, J. S. Flick, M. Johnston, and M. Carlson. 1997. Expression of the SUC2 gene of Saccharomyces cerevisiae is inducible by low levels of glucose. Yeast 13: 127-137.
  8. Özcan, S., J. Dover, and M. Johnston. 1998. Glucose sensing and signaling by two glucose receptors in the yeast S. cerevisiae. EMBO J. 17:2566-2573.
  9. Özcan, S., and M. Johnston. 1999. Function and regulation of yeast hexose transporters. Microbiol. Mol. Biol. Rev. 63:554-569.
  10. Özcan, S., A. L. Mosley, and B. K. Aryal. 2002. Functional expression and analysis of the pancreatic transcription factor PDX-1 in yeast. Biochem. Biophysical. Res. Comm. 295:724 –729.
  11. Özcan, S. 2002. Two different signals regulate repression and induction of gene expression by glucose. J. Biol. Chem. 277: 46993-46997.
  12. Mosley, A. L., and S. Özcan. 2003. Adenoviral gene transfer into beta cell lines. Methods Mol. Med. 83:73-79.
  13. Lakshmanan, J., J. S. Elmendorf and S. Özcan. 2003. Analysis of insulin-stimulated glucose uptake in differentiated 3T3-L1 adipocytes. Methods Mol. Med. 83:97-103.
  14. Mosley, A. L., J. Lakshmanan, B. K. Aryal, and S. Özcan. 2003. Glucose-mediated phosphorylation converts the transcription factor Rgt1 from a repressor to an activator. J. Biol. Chem. 278:10322-10327.
  15. Mosley, A. L., and S. Özcan. 2003. Glucose regulates insulin gene transcription by hyperacetylation of histone H4. J. Biol. Chem. 278:19660-19666.
  16. Lakshmanan, J., A. L. Mosley, and S. Özcan. 2003. Repression of transcription by Rgt1 in the absence of glucose requires Std1 and Mth1. Curr. Genet. 44:19-25.
  17. Mosley, A.L., M. L. Sampley, and S. Özcan. 2004. Glucose regulation of HXT gene expression in the yeast Saccharomyces cerevisia. Topics Curr. Genet. 7:259-275.
  18. Mosley, A. L., Corbett, J. A., and S. Özcan. 2004. Glucose regulation of insulin gene expression requires the recruitment of p300 by the beta-cell specific transcription factor Pdx-1. Mol. Endocrinol.18:2279-2290.
  19. Mosley, A. L., and S. Özcan. 2004. The pancreatic duodenal homeobox-1 protein (Pdx-1) interacts with histone deacetylases Hdac-1 and Hdac-2 on low levels of glucose. J. Biol. Chem. 279:54241-54247.
  20. Qian, Q., J. P. Williams, D. G. Karounos, and S. Özcan. 2005. Nitric oxide stimulates insulin release in liver cells expressing human insulin. Biochem. Biophysical. Res. Comm. 329:1329-1333.
  21. Finlin, B. S., A. L. Mosley, S. M. Crump, R. N. Correll, S. Özcan, J. Satin, and D. A. Andres. 2005. Regulation of L-type Ca2+ channel activity and insulin secretion by the Rem2 GTPase. J. Biol. Chem. 280:41864-41871.
  22. Andrali, S. S., P. Marz, S. Özcan. 2005. Ataxin-10 interacts with O-GlcNAc transferase OGT in pancreatic beta cells. Biochem. Biophysical. Res. Comm. 337:149-153.

Edited Books

  1. Özcan, S. 2003 (ed.): Diabetes Mellitus. Methods and Protocols. Methods Mol. Med. Vol 83; Humana Press, Totowa, New Jersey.

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